PRP can be used in most individuals and due to the autologus nature of PRP, the treatment is appropriate for minors with parental/guardian approval.
The following considerations can be utilized for target patients considering use of PRP:
- Platelet dysfunction syndrome
- Critical thrombocytopenia
- Hemodynamic instability
- Septicemia
- Local infection at the site of the procedure
- Patient unwilling to accept risks
- Tobacco use
- Recent fever or illness
- Cancer- especially hematopoietic or of bone
- HGB < 10 g/dl
- Platelet count < 105/ul
- Consistent use of NSAIDs within 48 hours of procedure
- Corticosteroid injection at treatment site within 1 month
- Systemic use of corticosteroids within 2 weeks